The cinchona alkaloid squaramide catalyzed asymmetric Pictet–Spengler reaction and related theoretical studies.

DOI Number:

10.1039/C7OB02606D
Link to literature

Reaction Category:

Cyclization | Cyclization | Further Cyclizations

MOP ID:

MOP_0000561

Educt:

N-protected 2-(1H-indol-3-yl)ethan-1-amine, aldehydes

Product:

N-protected (1R)-substituted 2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole

Catalyst:

3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione

Cas No:

1256245-79-0

Associated Product from Buchler GmbH:

Quinidine Base

Cas No:

56-54-2