Organocatalytic, Enantioselective Synthesis of Cyclohexadienone Containing Hindered Spirocyclic Ethers through an Oxidative Dearomatization/Oxa‐Michael Addition Sequence.
DOI Number:
10.1002/anie.201607039
Reaction Category:
MOP ID:
MOP_0000561
Educt:
(E)-5-(4-hydroxyphenyl)-1-(p-tolyl)pent-2-en-1-one, Iodobenzene diacetate
Product:
(S)-2-(2-oxo-2-(p-tolyl)ethyl)-1-oxaspiro[4.5]deca-6,9-dien-8-one
Catalyst:
3-[[(9R)-6′-methoxycinchonan-9-yl]amino]-4-[[(1R)-1-phenylethyl]amino]-3-cyclobutene-1,2-dione
Cas No:
2041793-45-5
Associated Product from Buchler GmbH:
Quinidine Base
Cas No:
56-54-2