Enantioselective organocatalytic oxa-Michael addition of oximes to β-CF 3-β-disubstituted nitroalkenes: efficient synthesis of β-amino-α-trifluoromethyl alcohols.
DOI Number:
10.1039/C3OB42329H
Reaction Category:
RXNO ID:
RXNO_0000009
Educt:
(Z)-1,3-dimethyl-5-(3,3,3-trifluoro-1-nitroprop-1-en-2-yl)benzene, 4-methoxybenzaldehyde oxime
Product:
(S)-4-methoxybenzaldehyde O-(2-(3,5-dimethylphenyl)-1,1,1-trifluoro-3-nitropropan-2-yl) oxime
Catalyst:
N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea
Cas No:
852913-16-7
Associated Product from Buchler GmbH:
Quinine Base
Cas No:
130-95-0