Asymmetric Synthesis of Cyclohexenone-Fused Isochromans via Quinidine-Catalyzed Domino Peroxyhemiacetalization/Oxa-Michael Addition/Desymmetrization Sequence.

DOI Number:

10.1021/acs.joc.2c00215
Link to literature

Reaction Category:

Cyclization | Desymmetrization | Further Cyclizations | Intramolecular cyclization | Michael Addition | Oxa-Michael Addition

MOP ID:

MOP_0000561

Educt:

2,5-cyclohexadienone-tethered aryl aldehydes, hydroperoxyalkanes

Product:

cyclohexenone-fused isochromans

Catalyst:

Quinidine Base

Cas No:

56-54-2

Associated Product from Buchler GmbH:

Quinidine Base

Cas No:

56-54-2