Diastereo- and enantioselective nitro-Mannich reaction of α-substituted nitroacetates to N-phosphoryl imines catalyzed by cinchona alkaloid thiourea organocatalysts.
DOI Number:
10.1039/C3OB40335A
Reaction Category:
RXNO ID:
RXNO_0000235
Educt:
N-phosphoryl imines, alpha-substituted nitroacetates
Product:
2,3-disubstituted methyl (2S,3S)-3-((diethoxyphosphoryl)amino)-2-nitro-propanoate
Catalyst:
N-[3,5-Bis(trifluoromethyl)phenyl]-N′-(9S)-cinchonan-9-ylthiourea
Cas No:
851477-18-4
Associated Product from Buchler GmbH:
Cinchonine Base
Cas No:
118-10-5