Asymmetric Construction of 4 H-Pyrano [3, 2-b] indoles via Cinchonine-Catalyzed 1, 4-Addition of 2-Ylideneoxindole with Malononitrile.

DOI Number:

10.1021/acs.joc.9b00430
Link to literature

Reaction Category:

[4+2]-Cycloaddition | Cascade reaction | Cycloaddition | Michael Addition | Oxa-Michael Addition

MOP ID:

MOP_0000565

Educt:

N/C-substituted (Z)-2-ethylideneindolin-3-one, malononitrile

Product:

N/C-substituted (R)-2-amino-4-methyl-4,5-dihydropyrano[3,2-b]indole-3-carbonitrile

Catalyst:

Cinchonine Base

Cas No:

118-10-5

Associated Product from Buchler GmbH:

Cinchonine Base

Cas No:

118-10-5