Probing α-Amino Aldehydes as Weakly Acidic Pronucleophiles: Direct Access to Quaternary α-Amino Aldehydes by an Enantioselective Michael Addition Catalyzed by Brønsted Bases.
DOI Number:
10.1002/chem.202004468
Reaction Category:
RXNO ID:
RXNO_0000009
Educt:
α-branched α-amino aldehydes, nitroolefins
Product:
α-amino aldehydes
Catalyst:
(2S)-N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-2-[[2-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3,4-dioxo-1-cyclobuten-1-yl]amino]-3,3-dimethyl Butanamide
Cas No:
2576590-75-3
Associated Product from Buchler GmbH:
Quinine Base
Cas No:
130-95-0