Enantioselective Michael addition using 4(3H)-pyrimidinone.
DOI Number:
10.1002/jccs.202200105
Reaction Category:
RXNO ID:
RXNO_0000009
Educt:
substituted methyl (E)-4-oxo-4-phenylbut-2-enoate, pyrimidin-4(3H)-one
Product:
substituted (R)-4-oxo-2-(6-oxopyrimidin-1(6H)-yl)-4-phenylbutanoate
Catalyst:
3-[[3,5-Bis(trifluoromethyl)phenyl]amino]- 4-[(9R)-cinchonan-9-ylamino]-3- cyclobutene-1,2-dione
Cas No:
1256245-82-5
Associated Product from Buchler GmbH:
Cinchonine Base
Cas No:
118-10-5