Preparation of Indolin-3-one-Containing 1,4-Naphthoquinone Derivatives via Organocatalytic Asymmetric Michael Addition Reaction.

DOI Number:

10.1021/acs.joc.4c00956
Link to literature

Reaction Category:

Michael | Michael Addition

RXNO ID:

RXNO_0000009

Educt:

substituted indolin-3-one, 2-hydroxynaphthalene-1,4-dione, acetyl chloride

Product:

substituted 1,4-dioxo-3-((3-oxoindolin-2-yl)methyl)-1,4-dihydronaphthalen-2-yl acetate

Catalyst:

3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione

Cas No:

1256245-84-7

Associated Product from Buchler GmbH:

Quinine Base

Cas No:

130-95-0