Quinidine-catalyzed enantioselective domino Michael addition/cyclization process: Synthesis of chiral 1, 4-dihydro-pyridine containing benzosultams.
DOI Number:
10.1016/j.mcat.2022.112165
Reaction Category:
MOP ID:
MOP_0000561
Educt:
substituted (E)-3-(prop-1-en-1-yl)benzo[d]isothiazole 1,1-dioxide, malononitrile
Product:
(9S)-substituted 7-amino--9H-benzo[4,5]isothiazolo[2,3-a]pyridine-8-carbonitrile 5,5-dioxide
Catalyst:
Quinidine Base
Cas No:
56-54-2
Associated Product from Buchler GmbH:
Quinidine Base
Cas No:
56-54-2