Urea‐and Thiourea‐Substituted Cinchona Alkaloid Derivatives as Highly Efficient Bifunctional Organocatalysts for the Asymmetric Addition of Malonate to Nitroalkenes: Inversion of Configuration at C9 Dramatically Improves Catalyst Performance.

DOI Number:

10.1002/anie.200501721

Reaction Category:

RXNO ID:

RXNO_0000009

Educt:

nitroalkenes, dimethyl malonate

Product:

substituted dimethyl 2-(2-nitroethyl)malonate

Catalyst:

N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-10,11-dihydro-6′-methoxy-cinchonan-9-yl]-Thiourea

Cas No:

852913-19-0

Cas No:

522-66-7