Highly enantioselective Michael addition of 1,3-dicarbonyl compounds to nitroalkenes catalyzed by designer chiral BINOL–quinine–squaramide: efficient access to optically active nitro-alkanes and their isoxazole derivatives.
DOI Number:
10.1016/j.tetasy.2013.08.010
Reaction Category:
RXNO ID:
RXNO_0000009
Educt:
nitroalkenes, 1,3-dicarbonyl compounds
Product:
nitroalkanes
Catalyst:
3-[[[(1S)-2,2′-dihydroxy[1,1′-binaphthalen]-3-yl]methyl]amino]-4-[[(9S)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione
Cas No:
1486483-03-7
Associated Product from Buchler GmbH:
Quinine Base
Cas No:
130-95-0