Molecular assembly of an achiral phosphine and a chiral primary amine: A highly efficient supramolecular catalyst for the enantioselective Michael reaction of aldehydes with maleimides.
DOI Number:
10.1002/asia.201300141
Reaction Category:
RXNO ID:
RXNO_0000009
Educt:
N-aryl substituted maleimide, α-disubstituted aldehyde
Product:
N,C-substituted (R)-2-(2,5-dioxopyrrolidin-3-yl)acetaldehyde
Catalyst:
triphenylphosphane, (9R)-Cinchonan-9-amine
Cas No:
168960-96-1
Associated Product from Buchler GmbH:
Cinchonine Base
Cas No:
118-10-5