Organocatalytic Enantioselective Michael-Addition of Malonic Acid Half-Thioesters to β-Nitroolefins: From Mimicry of Polyketide Synthases to Scalable Synthesis of g-Amino Acids.
DOI Number:
10.1002/adsc.201100458
Reaction Category:
RXNO ID:
RXNO_0000009
Educt:
(E)-(2-nitrovinyl)benzene, 3-((4-methoxyphenyl)thio)-3-oxopropanoic acid
Product:
S-(4-methoxyphenyl) (S)-4-nitro-3-phenylbutanethioate
Catalyst:
3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione
Cas No:
1256245-84-7
Associated Product from Buchler GmbH:
Quinine Base
Cas No:
130-95-0