Combination of Metal and Organic Catalysis: Highly Diastereo- and Enantioselective Construction of Fluorinated 2-Amino-cyclopenta[b]pyran Derivatives.
DOI Number:
10.1002/adsc.201500744
Reaction Category:
MOP ID:
MOP_0000562
Educt:
methyl (R,E)-3-benzylidene-1-fluoro-2-oxocyclopentane-1-carboxylate, malononitrile
Product:
methyl (4S,7R)-2-amino-3-cyano-7-fluoro-4-phenyl-4,5,6,7-tetrahydrocyclopenta[b]pyran-7-carboxylate
Catalyst:
3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4- [[(8α,9S)-6′-methoxycinchonan-9-yl]amino]- 3-Cyclobutene-1,2-dione
Cas No:
1256245-84-7
Associated Product from Buchler GmbH:
Quinine Base
Cas No:
130-95-0