Total Synthesis of (+)- and (−)-Calycanthine by Means of Thio-Urea-Catalyzed Sequential Michael Reactions of Bis-oxindoles.

DOI Number:

10.1021/acs.joc.4c00019
Link to literature

Reaction Category:

Michael | Michael Addition

RXNO ID:

RXNO_0000009

Educt:

bis-oxindoles, nitroethene

Product:

nitroalkylated bis-oxindoles

Catalyst:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-(8α,9S)-cinchonan-9-ylthiourea

Cas No:

890044-38-9

Associated Product from Buchler GmbH:

Cinchonidine Base

Cas No:

485-71-2