A practical synthesis of optically active δ-nitro-α-ketoesters and 4-cyclohexyl-proline catalyzed by chiral squamides.
![](https://www.buchler-gmbh.com/wp-content/uploads/Michael-Addition-5-5.jpg)
DOI Number:
10.1016/j.tetasy.2015.10.009
Reaction Category:
RXNO ID:
RXNO_0000009
Educt:
beta,gamma-unsaturated-alpha-ketoesters, t-butyl nitroacetate
Product:
delta-nitro-alpha-ketoesters
Catalyst:
3-[[(8α,9S)-6′-Methoxycinchonan-9-yl]amino]-4-(phenylamino)-3-cyclobutene-1,2-dione
Cas No:
1528740-10-4
Associated Product from Buchler GmbH:
Quinine Base
Cas No:
130-95-0