Highly enantioselective Michael addition of nitroalkanes to chalcones using chiral squaramides as hydrogen bonding organocatalysts.

DOI Number:

10.1021/ol102294g

Reaction Category:

RXNO ID:

RXNO_0000009

Educt:

alpha,beta unsaturated ketones, nitromethane

Product:

beta-(nitromethyl)-ketones

Catalyst:

3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4- [[(8α,9S)-6′-methoxycinchonan-9-yl]amino]- 3-Cyclobutene-1,2-dione

Cas No:

1256245-84-7

Cas No:

130-95-0