Highly enantioselective Michael addition of nitroalkanes to chalcones using chiral squaramides as hydrogen bonding organocatalysts.
DOI Number:
10.1021/ol102294g
Reaction Category:
RXNO ID:
RXNO_0000009
Educt:
alpha,beta unsaturated ketones, nitromethane
Product:
beta-(nitromethyl)-ketones
Catalyst:
3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4- [[(8α,9S)-6′-methoxycinchonan-9-yl]amino]- 3-Cyclobutene-1,2-dione
Cas No:
1256245-84-7
Associated Product from Buchler GmbH:
Quinine Base
Cas No:
130-95-0