Catalytic Enantioselective Synthesis of Tertiary Thiols From 5H‐Thiazol‐4‐ones and Nitroolefins: Bifunctional Ureidopeptide‐Based Brønsted Base Catalysis.
DOI Number:
10.1002/anie.201305644
Reaction Category:
RXNO ID:
RXNO_0000009
Educt:
5-methyl-2-(quinolin-2-yl)thiazol-4(5H)-one, (E)-(2-nitrovinyl)benzene
Product:
(R)-5-methyl-5-((S)-2-nitro-1-phenylethyl)-2-(quinolin-2-yl)thiazol-4(5H)-one
Catalyst:
9-Anthracenylmethyl N-[(1S)-1-[[[[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]carbonyl]amino]-2,2-dimethylpropyl]carbamate
Cas No:
1551121-36-8
Associated Product from Buchler GmbH:
Dihydroquinine Base
Cas No:
522-66-7