Organocatalyzed Asymmetric Vinylogous Addition of Oxazole-2(3H)-thiones to α, β-Unsaturated Ketones: An Additive-Free Approach for Diversification of Heterocyclic Scaffold.

DOI Number:

10.1021/acs.joc.7b02236

Reaction Category:

RXNO ID:

RXNO_0000009

Educt:

4-methyloxazole-2(3H)-thione, (E)-4-phenylbut-3-en-2-one

Product:

(R)-4-(4-methyl-2-thioxo-2,3-dihydrooxazol-5-yl)-4-phenylbutan-2-one

Catalyst:

(9R)-Cinchonan-9-amine

Cas No:

168960-96-1

Cas No:

118-10-5