Asymmetric Michael Additions of 4‑Hydroxycoumarin to β‑Nitrostyrenes with Chiral, Bifunctional Hydrogen-Bonding Catalysts.
DOI Number:
10.1021/acs.joc.5b02167
Reaction Category:
RXNO ID:
RXNO_0000009
Educt:
4-hydroxycoumarin, (E)-(2-nitrovinyl)benzene
Product:
(R)-4-hydroxy-3-(2-nitro-1-phenylethyl)-2H-chromen-2-one
Catalyst:
3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione
Cas No:
1256245-84-7
Associated Product from Buchler GmbH:
3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione
Cas No:
1256245-84-7