Diastereo- and Enantioselective Michael Addition of 3-Substituted Oxindoles to Trifluoromethyl-Substituted Nitro Olefins Catalyzed by a Cinchona-Alkaloid-Derived Squaramide.

DOI Number:

10.1002/ejoc.201301457

Reaction Category:

RXNO ID:

RXNO_0000009

Educt:

3-substituted oxindoles, (E)-3,3,3-trifluoro-1-nitroprop-1-ene

Product:

3-substituted-3-((R)-1,1,1-trifluoro-3-nitropropan-2-yl)oxindoles

Catalyst:

3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4- [[(8α,9S)-6′-methoxycinchonan-9-yl]amino]- 3-Cyclobutene-1,2-dione

Cas No:

1256245-84-7

Cas No:

130-95-0