Efficient Access to Trifluoromethyl Diarylpyrrolines and their N‐Oxides through Enantioselective Conjugate Addition of Nitromethane to β,β‐Disubstituted Enones.
DOI Number:
10.1002/anie.201301123
Reaction Category:
RXNO ID:
RXNO_0000009
Educt:
1,3-substituted (E)-4,4,4-trifluorobut-2-en-1-one, nitromethane
Product:
1,3-substituted (S)-4,4,4-trifluoro-3-(nitromethyl)-butan-1-one
Catalyst:
(9S)-1-[[3,5-bis(1,1-dimethylethyl)phenyl]methyl]-9-butoxy-6′-hydroxy-cinchonanium bromide
Cas No:
1452160-27-8
Associated Product from Buchler GmbH:
Cupreidine Base
Cas No:
70877-75-7