Enantioselective organocatalytic Michael addition of nitroalkanes and other nucleophiles to β-trifluoromethylated acrylamides.

DOI Number:

10.1021/cs300806w
Link to literature

Reaction Category:

Michael | Michael Addition

RXNO ID:

RXNO_0000009

Educt:

β-trifluoromethylated acrylamides, nitromethane

Product:

(R)-4-benzyl-3-((R)-4,4,4-trifluoro-3-(nitromethyl)butanoyl)oxazolidin-2-one

Catalyst:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′- methoxycinchonan-9-yl]thiourea

Cas No:

852913-25-8

Associated Product from Buchler GmbH:

Quinidine Base

Cas No:

56-54-2