Bifunctional Brønsted Base Catalyst Enables Regio-, Diastereo-, and Enantioselective Cα-Alkylation of β-Tetralones and Related Aromatic-Ring-Fused Cycloalkanones.
DOI Number:
10.1002/anie.201612332
Reaction Category:
RXNO ID:
RXNO_0000009
Educt:
α-monosubstituted β-tetralones, nitroolefins
Product:
α-disubstituted β-tetralones
Catalyst:
3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione
Cas No:
1256245-84-7
Associated Product from Buchler GmbH:
Quinine Base
Cas No:
130-95-0