Chiral Squaramide-Catalyzed Asymmetric Mannich Reactions for Synthesis of Fluorinated 3,3′-Bisoxindoles.

DOI Number:

10.1002/adsc.201800513

Reaction Category:

RXNO ID:

RXNO_0000032

Educt:

substituted 3-fluoro-indolin-2-ones, substituted benzo[e][1,2,3]oxathiazine 2,2-dioxides

Product:

substituted (S)-3-((R)-2,2-dioxido-3,4-dihydrobenzo[e][1,2,3]oxathiazin-4-yl)-3-fluoroindolin-2-ones

Catalyst:

(8α,9R)-9-(Phenylmethoxy) cinchonan-6′-ol

Cas No:

838821-39-9

Cas No:

524-63-0