Diastereo-and enantioselective Mannich/cyclization cascade reaction of isocyanoacetates with cyclic sulfamide ketimines by cinchona alkaloid squaramide/AgOAc cooperative catalysis.
DOI Number:
10.1039/C8OB01090K
Reaction Category:
RXNO ID:
RXNO_0000032
Educt:
substituted 2-isocyanoacetate, 4-substituted 2-methyl-1,2,5-thiadiazol-3(2H)-one 1,1-dioxide
Product:
substituted (4S)-2-methyl-3-oxo-2,3,3a,4-tetrahydroimidazo[1,5-b][1,2,5]thiadiazole-4-carboxylate 1,1-dioxide
Catalyst:
silver acetate, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4- [[(8α,9S)-10,11-dihydro-6′-methoxycinchonan- 9-yl]amino]-3-Cyclobutene-1,2-dione
Cas No:
1352957-59-5
Associated Product from Buchler GmbH:
Dihydroquinine Base
Cas No:
522-66-7