Enantioselective anti-Mannich reaction catalyzed by modularly designed organocatalysts.

DOI Number:

10.1016/j.tet.2018.09.006
Link to literature

Reaction Category:

Mannich | Mannich

RXNO ID:

RXNO_0000032

Educt:

ketones, ethyl (E)-2-((4-methoxyphenyl)imino)acetate

Product:

3,3,4-trisubstituted ethyl (R)-2-((4-methoxyphenyl)amino)-4-oxobutanoate

Catalyst:

(R)-pyrrolidine-3-carboxylic acid, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-25-8

Associated Product from Buchler GmbH:

Quinidine Base

Cas No:

56-54-2