Asymmetric organocatalytic direct Mannich reaction of acetylacetone and isatin derived ketimines: Low catalyst loading in chiral cinchona-squaramides.

DOI Number:

10.1016/j.tetlet.2017.12.081

Reaction Category:

RXNO ID:

RXNO_0000032

Educt:

isatin derived ketimines, acetylacetone

Product:

substituted (S)-(3-(2,4-dioxopentan-3-yl)-2-oxoindolin-3-yl)carbamate

Catalyst:

3-[[(8α,9S)-6′-Methoxycinchonan-9-yl]amino]-4-(tricyclo[3.3.1.13,7]dec-2-ylamino)-3-cyclobutene-1,2-dione

Cas No:

1877237-86-9

Cas No:

130-95-0