Chiral Squaramide-Catalyzed Enantioselective Decarboxylative Addition of β-Keto Acids to Isatin Imines.

DOI Number:

10.1002/adsc.201700011

Reaction Category:

RXNO ID:

RXNO_0000032

Educt:

benzoylacetic acid, tert-butyl (E)-(1-benzyl-2-oxoindolin-3-ylidene)carbamate

Product:

tert-butyl (S)-(1-benzyl-2-oxo-3-(2-oxo-2-phenylethyl)indolin-3-yl)carbamate

Catalyst:

3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione

Cas No:

1256245-84-7

Cas No:

130-95-0