Asymmetric Mannich reactions catalyzed by cinchona alkaloid thiourea: Enantioselective one-pot synthesis of novel β-amino ester derivatives.

DOI Number:

10.1016/j.tetasy.2011.02.029
Link to literature

Reaction Category:

Mannich | Mannich

RXNO ID:

RXNO_0000032

Educt:

5-chlorobenzo[d]oxazol-2-amine, aldehydes, malonates

Product:

β-amino ester derivatives

Catalyst:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-16-7

Associated Product from Buchler GmbH:

Quinine Base

Cas No:

130-95-0