Bifunctional Brønsted Base Catalyzed Mannich Reaction of β‐Alkoxy α‐Keto Amides: Stereocontrolled Entry to Functionalized Amino Diols.

DOI Number:

10.1002/chem.201802550

Reaction Category:

RXNO ID:

RXNO_0000032

Educt:

α-ketoamides, p-nosylimines

Product:

substituted 3-hydroxy-4-((4-nitrophenyl)sulfonamido)-2-oxobutanamide

Catalyst:

N-[3,5-bis(trifluoromethyl)phenyl]-3-[[2-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3,4-dioxo-1-cyclobuten-1-yl]amino]-N-(phenylmethyl)-5-(trifluoromethyl)-benzamide

Cas No:

2241441-31-4

Cas No:

130-95-0