Asymmetric Mannich Reaction of Isatin-Derived Ketimines with α-Fluoroindanones Catalyzed by a Chiral Phase-Transfer Catalyst.

DOI Number:

10.1021/acs.joc.3c02668
Link to literature

Reaction Category:

Mannich | Mannich

RXNO ID:

RXNO_0000032

Educt:

α-fluoroindanones, isatin-derived N-Boc-ketimines

Product:

3-substituted 3-amino-2-oxindoles

Catalyst:

9-hydroxy-1-[(4-iodophenyl)methyl]-6′-methoxy-(8α,9R)-cinchonanium bromide

Cas No:

3033782-95-2

Associated Product from Buchler GmbH:

Quinine Base

Cas No:

130-95-0