Development of a diastereoselective phosphorylation of a complex nucleoside via dynamic kinetic resolution.

DOI Number:

10.1021/acs.joc.5b00392

Reaction Category:

Educt:

substituted (hydroxy(naphthalen-1-yloxy)phosphoryl)-L-alaninate, complex nucleosides

Product:

substituted ((S)-(((2R,3R,4R,5R)-5-(2-amino-6-methoxy-9H-purin-9-yl)-3,4-dihydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(naphthalen-1-yloxy)phosphoryl)-L-alaninate

Catalyst:

Quinine Base

Cas No:

130-95-0

Cas No:

130-95-0