Asymmetric Synthesis of Trifluoromethylated Amines via Catalytic Enantioselective Isomerization of Imines.

DOI Number:

10.1021/ja306771n
Link to literature

Reaction Category:

Isomerization

MOP ID:

MOP_0000789

Educt:

(E)-2,2,2-trifluoro-N-(4-nitrobenzyl)-1-phenylethan-1-imines

Product:

(R,E)-1-(4-nitrophenyl)-N-(2,2,2-trifluoro-1-phenylethyl)methanimines

Catalyst:

(8α,9R)-2′-Chloro-10,11-dihydro-6′-methoxycinchonan-9-ol

Cas No:

105879-89-8

Associated Product from Buchler GmbH:

Dihydroquinine Base

Cas No:

522-66-7