Synthesis of an advanced precursor of Rivastigmine: Cinchona-derived quaternary ammonium salts as organocatalysts for stereoselective imine reductions.
DOI Number:
10.1016/j.tetlet.2015.08.086
Reaction Category:
RXNO ID:
RXNO_0000290
Educt:
(S,E)-1-(3-(benzyloxy)phenyl)-N-(1-phenylethyl)ethan-1-imine, trichlorosilane
Product:
(S)-1-(3-(benzyloxy)phenyl)-N-((S)-1-phenylethyl)ethan-1-amine
Catalyst:
(8α,9S)-1-(phenylmethyl)-9-[(2-pyridinylcarbonyl)amino]-Cinchonanium bromide
Cas No:
1809788-51-9
Associated Product from Buchler GmbH:
Cinchonidine Base
Cas No:
485-71-2