Asymmetric synthesis of alkyl 5-oxotetrahydrofuran-2-carboxylates by enantioselective hydrogenation of dialkyl 2-oxoglutarates over cinchona modified Pt/Al2O3 catalysts.
DOI Number:
10.1039/b9000390p
Reaction Category:
MOP ID:
MOP_0000589
Educt:
diethyl 2-oxopentanedioate, hydrogen, p-toluenesulfonic acid
Product:
ethyl (R)-5-oxotetrahydrofuran-2-carboxylate
Catalyst:
platinum/aluminiumoxide, (8α,9R)-10,11-Dihydro-9-methoxycinchonan
Cas No:
129960-94-7
Associated Product from Buchler GmbH:
Dihydrocinchonidine Base
Cas No:
485-64-3