A New Class of Urea-Substituted Cinchona Alkaloids Promote Highly Enantioselective Nitroaldol reactions of Trifluoromethyl-ketones.
DOI Number:
10.1021/ol103089j
Reaction Category:
RXNO ID:
RXNO_0000086
Educt:
1,1,1-trifluoro-3-phenylpropan-2-one, nitromethane
Product:
(S)-1,1,1-trifluoro-2-nitro-3-phenylpropan-2-ol
Catalyst:
N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9R)-9-[[[[3,5-bis(trifluoromethyl)phenyl]amino]carbonyl]oxy]-10,11-dihydro-6′-methoxycinchonan-5′-yl]-urea
Cas No:
1269656-94-1
Associated Product from Buchler GmbH:
Dihydroquinine Base
Cas No:
522-66-7