Regio- and Enantioselective Friedel–Crafts Benzhydrylation of Indoles in Carbocyclic Ring with ortho-Quinomethanes: Access to Chiral Diarylindolylmethanes.
DOI Number:
10.1021/acs.joc.9b03479
Reaction Category:
RXNO ID:
RXNO_0000369
Educt:
2-Methoxy-6-[[(4-methylphenyl)sulfonyl]phenylmethyl]phenol, 7-Hydroxyindole
Product:
(R)-6-((2-hydroxy-3-methoxyphenyl)(phenyl)methyl)-1H-indol-7-ol
Catalyst:
3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione
Cas No:
1352957-59-5
Associated Product from Buchler GmbH:
Dihydroquinine Base
Cas No:
522-66-7