Asymmetric Friedel− Crafts Alkylation of Indoles with α,β‐unsaturated Trifluoromethyl Ketones Using a Squaramide Organocatalyst.
DOI Number:
10.1002/ajoc.202200403
Reaction Category:
RXNO ID:
RXNO_0000046
Educt:
1H-indole, α,β‐unsaturated trifluoromethyl ketones
Product:
4S-substituted 1,1,1-trifluoro-4-(1H-indol-3-yl)butan-2-one
Catalyst:
3-[[3,5-bis(1,1-dimethylethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione
Cas No:
2837196-65-1
Associated Product from Buchler GmbH:
Quinine Base
Cas No:
130-95-0