Enantioselective synthesis of cis-3-fluoropiperidin-4-ol, a building block for medicinal chemistry.
DOI Number:
10.1021/jo401352z
Reaction Category:
MOP ID:
MOP_0000553
Educt:
protected piperidin-4-one, N-fluoro-N-(phenylsulfonyl)benzenesulfonamide
Product:
cis-3-fluoropiperidin-4-ol
Catalyst:
trichloroacetic acid, (8α,9S)-6′-Methoxycinchonan-9-amine
Cas No:
168960-95-0
Associated Product from Buchler GmbH:
Quinine Base
Cas No:
130-95-0