One-pot Fluorination and Organocatalytic Robinson Annulation for Asymmetric Synthesis of Mono- and Difluorinated Cyclohexenones.
DOI Number:
10.3390/molecules23092251
Reaction Category:
MOP ID:
MOP_0000553
Educt:
ethyl 3-oxobutanoate, 1-(chloromethyl)-4-fluoro-1,4-diazabicyclo[2.2.2]octane-1,4-diium, (E)-3-(4-bromophenyl)-1-phenylprop-2-en-1-one
Product:
(1S,6S)-6-(4-bromophenyl)-1-fluoro-2-oxo-4-phenyl-3-Cyclohexene-1-carboxylic acid ethyl ester
Catalyst:
(8α,9S)-10,11-Dihydro-6′-methoxycinchonan-9-amine
Cas No:
852913-53-2
Associated Product from Buchler GmbH:
Dihydroquinine Base
Cas No:
522-66-7