Catalytic, Asymmetric α-Fluorination of Acid Chlorides: Dual Metal−Ketene Enolate Activation.
DOI Number:
10.1021/ja807792c
Reaction Category:
MOP ID:
MOP_0000553
Educt:
2-(4-methoxyphenyl)acetyl chloride, tert-butyl (S)-2-(hydroxymethyl)pyrrolidine-1-carboxylate, N-fluoro-N-(phenylsulfonyl)benzenesulfonamide
Product:
tert-butyl (S)-2-(((R)-2-fluoro-2-(4-methoxyphenyl)acetoxy)methyl)pyrrolidine-1-carboxylate
Catalyst:
Dichloro[1,3-bis(diphenylphosphino)propane]nickel, 6′-methoxy-(9S)-Cinchonan-9-ol-9-benzoate
Cas No:
60723-45-7
Associated Product from Buchler GmbH:
Quinidine Base
Cas No:
56-54-2