Phase-transfer catalyzed asymmetric Darzens reaction of cyclic a-chloro ketones.

DOI Number:

10.1039/A808321E
Link to literature

Reaction Category:

Epoxidation

MOP ID:

MOP_0000671

Educt:

3,3-dimethylbutanal, 2-chloro-3,4-dihydronaphthalen-1(2H)-one

Product:

(2S,3'R)-3'-neopentyl-3,4-dihydro-1H-spiro[naphthalene-2,2'-oxiran]-1-one

Catalyst:

9-hydroxy-1-[[4-(trifluoromethyl)phenyl]methyl]-(9S)-Cinchonanium bromide

Cas No:

95088-20-3

Associated Product from Buchler GmbH:

Cinchonine Base

Cas No:

118-10-5