Organocatalytic domino annulation of in situ generated tert-butyl 2-hydroxybenzylidenecarbamates with 2-isothiocyanato-1-indanones for synthesis of bridged and fused ring heterocycles.

DOI Number:

10.1039/d1qo00626f

Reaction Category:

MOP ID:

MOP_0000562

Educt:

substituted 2-isothiocyanato-2,3-dihydro-1H-inden-1-one, substituted tert-butyl ((2-hydroxyphenyl)(tosyl)methyl)carbamate

Product:

substituted tert-butyl ((4bS,10R,10aR)-13-thioxo-10H,11H-4b,10a-(epiminomethanoimino)indeno[1,2-b]chromen-10-yl)carbamate

Catalyst:

N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-10,11-dihydro-6′-methoxy-cinchonan-9-yl]-Thiourea

Cas No:

852913-19-0

Cas No:

522-66-7