Catalytic asymmetric desymmetrization of cyclopentendiones via Diels–Alder reaction of 3-Hydroxy-2-pyrones: construction of multifunctional bridged tricyclic lactones.
DOI Number:
10.1021/acs.orglett.7b02107
Reaction Category:
RXNO ID:
RXNO_0000006
Educt:
4,5-substitutded-3-hydroxy-2H-pyran-2-one, 2-substituted-cyclopent-4-ene-1,3-dione
Product:
2,5,6-substituted (4R,7R,7aR)-7-hydroxy-3a,4,7,7a-tetrahydro-1H-4,7-(epoxymethano)indene-1,3,8(2H)-trione
Catalyst:
N-(8α,9S)-cinchonan-9-yl-N′-[(1S,2S)-2-hydroxy-1,2-diphenylethyl]-thiourea
Cas No:
2126821-30-3
Associated Product from Buchler GmbH:
Cinchonidine Base
Cas No:
485-71-2