A formal catalytic asymmetric synthesis of (+)-biotin with modified cinchona alkaloids.

DOI Number:

10.1055/s-2001-16748
Link to literature

Reaction Category:

Desymmetrization

Educt:

cyclic anhydrides, methanol

Product:

(2R,3S)-4-methoxy-2,3-dimethyl-4-oxobutanoic acid

Catalyst:

1,4-Bis[(9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]-9,10-anthracenedione

Cas No:

176298-44-5

Associated Product from Buchler GmbH:

Dihydroquinidine Base

Cas No:

1435-55-8