A new reagent for the preparation of chiral HMGA (3-hydroxy-3-methylglutaric acid) esters and amides. Synthesis of (R)- and (S)-β-carboxymethyl-β-methyl-β-lactones by asymmetric desymmetrization of HMGA anhydride.
DOI Number:
10.1016/0040-4039(96)00274-2
Reaction Category:
Educt:
4-hydroxy-4-methyldihydro-2H-pyran-2,6(3H)-dione
Product:
(R)-2-(2-methyl-4-oxooxetan-2-yl)acetic acid
Catalyst:
Dihydroquinine Base
Cas No:
522-66-7
Associated Product from Buchler GmbH:
Dihydroquinine Base
Cas No:
522-66-7