Pilot-plant preparation of 3, 4-dihydropyridin-2-one derivatives, the core structures of P2X7 receptor antagonists.
DOI Number:
10.1021/op1000447
Reaction Category:
Educt:
4-(4-fluorophenyl)dihydro-2H-pyran-2,6(3H)-dione, methanol
Product:
(R)-3-(4-fluorophenyl)-5-methoxy-5-oxopentanoic acid
Catalyst:
N-[(8α,9S)-6′-Methoxycinchonan-9-yl]-3,5-bis(trifluoromethyl)benzenesulfonamide
Cas No:
1092116-26-1
Associated Product from Buchler GmbH:
N-[(8α,9S)-6′-Methoxycinchonan-9-yl]-3,5-bis(trifluoromethyl)benzenesulfonamide
Cas No:
1092116-26-1