Highly enantioselective decarboxylative protonation of α-aminomalonates mediated by thiourea Cinchona alkaloid derivatives: Access to both enantiomers of cyclic and acyclic α-aminoacids.

DOI Number:

10.1021/ol070712v

Reaction Category:

Educt:

substituted 2-(ethoxycarbonyl)-4-oxopentanoic acid

Product:

substituted ethyl 4-oxopentanoate

Catalyst:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-25-8

Associated Product from Buchler GmbH:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-25-8